FMK-MEA
FMK-MEA is a potent and selective p90 Ribosomal S6 Kinase (RSK) inhibitor.
Product Specifications
CAS Number
[1414811-15-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ribosomal S6 Kinase (RSK)
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/FMK-MEA.html
Concentration
10mM
Purity
99.40
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FCC(C1=C(C2=CC=C(C)C=C2)C3=C(N)N=CN=C3N1CCCNCCOC)=O
Molecular Formula
C21H26FN5O2
Molecular Weight
399.46
Precautions
H302, H315, H319, H335
References & Citations
[1]Li D, et al. The prometastatic ribosomal S6 kinase 2-cAMP response element-binding protein (RSK2-CREB) signaling pathway up-regulates the actin-binding protein fascin-1 to promote tumor metastasis. J Biol Chem. 2013 Nov 8;288 (45) :32528-38.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
RSK2
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
382268 96 Tests
CD34 (Cluster Of Differentiation 34) BioAssayTM ELISA Kit (Human) discontinued
Sign In for Pricing
View Details 
127240-Biotin 100 µL
GCNT2 (N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, Isoform A, N-acetylglucosaminyltransferase, I-branching Enzyme, IGNT, GCNT5, II, NACGT1) (Biotin)
Sign In for Pricing
View Details TRI-B43S1 24T
Duck-derived Nucleic Acid Detection Kit (Fluorescence PCR)
Sign In for Pricing
View Details GTR15087440 1 Vial
Lentiviral human SPCS3 shRNA (UAS) - Lentiviral human SPCS3 shRNA (UAS, GFP) (25)
Sign In for Pricing
View Details