FMK-MEA

FMK-MEA is a potent and selective p90 Ribosomal S6 Kinase (RSK) inhibitor.

Product Specifications

CAS Number

[1414811-15-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Ribosomal S6 Kinase (RSK)

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/FMK-MEA.html

Concentration

10mM

Purity

99.40

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FCC(C1=C(C2=CC=C(C)C=C2)C3=C(N)N=CN=C3N1CCCNCCOC)=O

Molecular Formula

C21H26FN5O2

Molecular Weight

399.46

Precautions

H302, H315, H319, H335

References & Citations

[1]Li D, et al. The prometastatic ribosomal S6 kinase 2-cAMP response element-binding protein (RSK2-CREB) signaling pathway up-regulates the actin-binding protein fascin-1 to promote tumor metastasis. J Biol Chem. 2013 Nov 8;288 (45) :32528-38.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

RSK2

Available Sizes

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