RIOK2 Human Protein

<strong> RIOK2 Human Protein</strong>_x000D_ <strong>Catalog number:</strong> B2017082_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 25 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 63.1 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80C_x000D_ <strong>Keywords:</strong> RIOK2 Human Protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Matsuzaki Y, Naito Y, Miura N, Mori T, Watabe Y, Yoshimoto S, Shibahara T, Takano M, Honda K. RIOK2 Contributes to Cell Growth and Protein Synthesis in Human Oral Squamous Cell Carcinoma Curr Oncol. 2022 Dec 26;30(1):381-391._x000D_ 2: Ghosh S, Raundhal M, Myers SA, Carr SA, Chen X, Petsko GA, Glimcher LH. Identification of RIOK2 as a master regulator of human blood cell development Nat Immunol. 2022 Jan;23(1):109-121._x000D_ 3: Raundhal M, Ghosh S, Myers SA, Cuoco MS, Singer M, Carr SA, Waikar SS, Bonventre JV, Ritz J, Stone RM, Steensma DP, Regev A, Glimcher LH. Blockade of IL-22 signaling reverses erythroid dysfunction in stress-induced anemias Nat Immunol. 2021 Apr;22(4):520-529._x000D_ 4: Cerezo EL, Houles T, Lié O, Sarthou MK, Audoynaud C, Lavoie G, Halladjian M, Cantaloube S, Froment C, Burlet-Schiltz O, Henry Y, Roux PP, Henras AK, Romeo Y. RIOK2 phosphorylation by RSK promotes synthesis of the human small ribosomal subunit PLoS Genet. 2021 Jun 14;17(6):e1009583._x000D_ 5: Messling JE, Peña-Rømer I, Moroni AS, Bruestl S, Helin K. RIO-kinase 2 is essential for hematopoiesis PLoS One. 2024 Apr 2;19(4):e0300623._x000D_ 6: Wang J, Varin T, Vieth M, Elkins JM. Crystal structure of human RIOK2 bound to a specific inhibitor Open Biol. 2019 Apr 26;9(4):190037._x000D_ 7: Liu K, Chen HL, Wang S, Gu MM, Chen XM, Zhang SL, Yu KJ, You QS. High Expression of RIOK2 and NOB1 Predict Human Non-small Cell Lung Cancer Outcomes Sci Rep. 2016 Jun 27;6:28666._x000D_ 8: Liu K, Chen H, You Q, Ye Q, Wang F, Wang S, Zhang S, Yu K, Li W, Gu M. miR‑145 inhibits human non‑small-cell lung cancer growth by dual-targeting RIOK2 and NOB1 Int J Oncol. 2018 Jul;53(1):257-265._x000D_ 9: Ouyang Y, Si H, Zhu C, Zhong L, Ma H, Li Z, Xiong H, Liu T, Liu Z, Zhang Z, Zhang ZM, Cai Q. Discovery of 8-(6-Methoxypyridin-3-yl)-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)-1,5-dihydro-4H-[1,2,3]triazolo[4,5-c]quinolin-4-one (CQ211) as a Highly Potent and Selective RIOK2 Inhibitor J Med Chem. 2022 Jun 9;65(11):7833-7842._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/37838312">10: Kumar R, Malik MZ, Thanaraj TA, Bagabir SA, Haque S, Tambuwala M, Haider S. A computational biology approach to identify potential protein biomarkers and drug targets for sporadic amyotrophic lateral sclerosis Cell Signal. 2023 Dec;112:110915. </a>_x000D_ _x000D_ <strong>Products Related to RIOK2 Human Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>