Citicoline (sodium)
Citicoline sodium is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline sodium inhibits reactive oxygen species (ROS) and apoptosis. Citicoline sodium can be used for neurological disease and hearing loss study[1][2][3].
Product Specifications
CAS Number
33818-15-4
Product Name Alternative
Cytidine diphosphate-choline (sodium) ; CDP-Choline (sodium) ; Cytidine 5'-diphosphocholine (sodium)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Caspase; Endogenous Metabolite; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Neuroscience-Neurodegeneration
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Cytidoline_sodium_salt.html
Purity
99.60
Solubility
DMSO : < 1 mg/mL|H2O : ≥ 100 mg/mL
Smiles
NC(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OCC[N+](C)(C)C)([O-])=O)(O[Na])=O)O2)=NC1=O
Molecular Formula
C14H25N4NaO11P2
Molecular Weight
510.31
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Caspase 3; Caspase 8; Caspase 9; Human Endogenous Metabolite; Microbial Metabolite
Citation 01
Int J Biol Macromol. 2025 Jan 5:139536.|bioRxiv. 2025 April 09.|Nat Neurosci. 2023 Apr;26 (4) :542-554.|Patent. US20240269160A1.
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