PROTAC GPX4 degrader-1
Product Specifications
UNSPSC Description
PROTAC GPX4 degrader-1 (DC-2) is a PROTAC-based GPX4 degrader, with a DC50 of 0.03 μM in HT1080 cells[1].
Target Antigen
Ferroptosis; Glutathione Peroxidase; PROTACs
Type
Reference compound
Related Pathways
Apoptosis;Metabolic Enzyme/Protease;PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-gpx4-degrader-1.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1CCN(C(C2=CC=C(C=C2)OCC(N3CCC(CC3)CN4CCN(CCCNC5=CC=CC(C(N6C7C(NC(CC7)=O)=O)=O)=C5C6=O)CC4)=O)C8=CC=C(C=C8)Cl)CC1)C9=NOC(C)=C9[N+]([O-])=O
Molecular Weight
993.50
References & Citations
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149236/PROTAC-GPX4-degrader-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149236/PROTAC-GPX4-degrader-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2916433-81-1
Available Sizes
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