SIRT2 Rabbit mAb
Product Specifications
Gene Name
[SIRT2]
NCBI Gene ID
22933
Reactivity
Human, Rat
Storage Conditions
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycle.
Specificity
Isoform 1 is expressed in heart, liver and skeletal muscle, weakly expressed in the cortex. Isoform 2 is strongly expressed in the cortex, weakly expressed in heart and liver. Weakly expressed in several malignancies including breast, liver, brain, kidney and prostate cancers compared to normal tissues. Weakly expressed in glioma cell lines compared to normal brain tissues (at protein level). Widely expressed. Highly expressed in heart, brain and skeletal muscle, while it is weakly expressed in placenta and lung. Down-regulated in many gliomas suggesting that it may act as a tumor suppressor gene in human gliomas possibly through the regulation of microtubule network.
Other Gene Names
[SIRT2; SIRT2; SIR2; SIR2L; SIR2L2; SIR2L; SIR2L2]
Short Name
[SIRT2]
Other Product Names
[NAD-dependent protein deacetylase sirtuin-2 isoform 3; NAD-dependent protein deacetylase sirtuin-2; NAD-dependent protein deacetylase sirtuin-2; sirtuin type 2; SIR2-like protein 2; sir2-related protein type 2; silent information regulator 2; regulatory protein SIR2 homolog 2; NAD-dependent deacetylase sirtuin-2; sirtuin 2; Regulatory protein SIR2 homolog 2; SIR2-like protein 2]
NCBI GI Number
300797705
NCBI Accession Number
NP_001180215.1
NCBI GB Accession Number
NM_001193286.1
Uniprot Accession Number
Q8IXJ6
Available Sizes
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