Tenacigenin B
Tenacigenin B is a steroid that can be isolated from the genus Alocasia. Tenacigenin B has anti-tumor effects on lymphoma via regulation of Aurora-A[1][2].
Product Specifications
CAS Number
80508-42-5
UNSPSC
12352005
Target
Aurora Kinase
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tenacigenin-b.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@]3(CC[C@H]2C(C)=O)[C@]4([C@@]([C@@H]([C@H]1O)O)([H])[C@@]5([C@@](C[C@H](CC5)O)([H])CC4)C)O3
Molecular Formula
C21H32O5
Molecular Weight
364.48
References & Citations
[1]Peng W, et al. The cytotoxic and tyrosine kinase inhibitory properties of C21 steroids and iridoids from the tubers of Alocasia cucullata. J Nat Med. 2016 Jul;70 (3) :602-9.|[2]Dai X, et al. Tenacigenin B Has Anti-Tumor Effect in Lymphoma by In Vitro and In Vivo Study. Med Sci Monit. 2019 Sep 1;25:6563-6573.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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