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Cucurbitacin IIa (Standard)

Cucurbitacin IIa (Standard) is the analytical standard of Cucurbitacin IIa. This product is intended for research and analytical applications. Cucurbitacin IIa is a triterpene isolated from Hemsleya amalils Diels, induces apoptosis of cancer cells, reduces expression of survivin, reduces phospho-Histone H3 and increases cleaved PARP in cancer cells[1].

Product Specifications

CAS Number

58546-34-2

Product Name Alternative

Hemslecin A (Standard)

UNSPSC

12352211

Target

Apoptosis; Reference Standards; Survivin

Type

Reference Standards

Related Pathways

Apoptosis; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cucurbitacin-iia-standard.html

Smiles

C[C@@]([C@@](CC=C1[C@@]2([H])C[C@H](O)[C@@H](O)C1(C)C)([H])[C@@]2(C)C3=O)(C[C@@H](O)[C@]4([H])[C@@](C)(O)C(CCC(C)(C)OC(C)=O)=O)[C@@]4(C3)C

Molecular Formula

C32H50O8

Molecular Weight

562.73

References & Citations

[1]Boykin C, et al. Cucurbitacin IIa: a novel class of anti-cancer drug inducing non-reversible actin aggregation and inhibiting survivin independent of JAK2/STAT3 phosphorylation. Br J Cancer. 2011 Mar 1;104 (5) :781-9.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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