Protein deglycase DJ-1 against-1

Protein deglycase DJ-1 against-1, a DJ-1-binding compound, dependently targets DJ1. Protein deglycase DJ-1 against-1 penetrates through the blood brain barrier (BBB) . Protein deglycase DJ-1 against-1 is used as a neuroprotective agent and has the potential for Parkinson's disease research[1].

Product Specifications

CAS Number

[724737-74-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/protein-deglycase-dj-1-against-1.html

Purity

99.83

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(NC1=CC=C(C2=CN3C=CC=C(C)C3=N2)C=C1)C4=CC(OC)=C(OC)C(OC)=C4

Molecular Formula

C24H23N3O4

Molecular Weight

417.46

Precautions

H302, H315, H319, H335

References & Citations

[1]Kazuko Takahashi-Niki, et al. DJ-1-dependent protective activity of DJ-1-binding compound no. 23 against neuronal cell death in MPTP-treated mouse model of Parkinson's disease.