Kindlin-1/KIND1
Product Specifications
Gene Name
[FERMT1]
NCBI Gene ID
55612
Reactivity
Human
Storage Conditions
Antibody with azide: store at 2 to 8°C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Kindlin-1 (also known as KIND1, KINDLERIN, UNC112-RELATED PROTEIN 1 (URP1) is an important component of cell-extracellular matrix adhesion. Kindlin-1 is involved in cell adhesion, possibly via its interaction with integrins and may mediate TGF-beta 1 signaling during tumor progression. Kindlin-1 has been shown to be significantly upregulated in lung and colon carcinomas. Mutations in the kindlin-1 gene, FERMT1, causes Kindler syndrome. Kindler syndrome is an autosomal recessive disorder characterized by neonatal blistering, sun sensitivity, atrophy, abnormal pigmentation and fragility of the skin. We have developed monoclonal anti-kidlin-1 antibodies. This monoclonal antibody recognizes kindlin-1 in multiple assays including Western blotting, immunoprecipitation, immunohistochemical and immunofluorescent staining.
Other Gene Names
[FERMT1; FERMT1; URP1; KIND1; DTGCU2; UNC112A; C20orf42; C20orf42; KIND1; URP1]
Short Name
[Kindlin-1/KIND1]
Other Product Names
[fermitin family homolog 1; Fermitin family homolog 1; fermitin family homolog 1; fermitin family member 1; Kindlerin; Kindlin syndrome protein; Kindlin-1; Unc-112-related protein 1]
NCBI GI Number
116686114
NCBI Accession Number
NP_060141.3
NCBI GB Accession Number
NP_060141.3
Uniprot Accession Number
Q9BQL6
Available Sizes
Curated Selection
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