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Apolipoprotein A4/apoA-IV

Product Specifications

Gene Name

[APOA4]

NCBI Gene ID

337

Reactivity

Human

Storage Conditions

Antibody with azide: store at 2 to 8 degree C.<br>Antibody without azide: store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

Apolipoproteins are protein components of plasma lipoproteins. The human apoA-I gene encodes a single chain, 243 amino acid protein which promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in the plasma. It can function as a cofactor for lecithin cholesterolacyltransferase (LCAT), which is responsible for the formation of most plasma cholesteryl esters. The human apoA-II gene encodes the second most abundant protein of HDL particles, where it influences plasma levels of free fatty acids (FFA). The human apoA-IV gene encodes a 396 amino acid preprotein, which after proteolytic processing is secreted from the intestine in association with chylomicron particles. ApoA-IV is a potent activator of LCAT in vitro. The human apoA-V gene encodes a 366 amino acid protein that is believed to be an important determinant of plasma triglyceride levels.

Other Gene Names

[APOA4; APOA4; Apo-AIV; ApoA-IV]

Short Name

[Apolipoprotein A4/apoA-IV]

Other Product Names

[Apolipoprotein A-IV; Apolipoprotein A-IV; apolipoprotein A-IV; apolipoprotein A4; Apolipoprotein A4]

NCBI GI Number

93163358

NCBI Accession Number

P06727.3

Uniprot Accession Number

P06727

Available Sizes

Curated Selection

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