What is the catalog number for EME1?

The catalog number for EME1 is MBS4381653.

What sizes are available for EME1?

EME1 is available in the following size(s): 0.02 mg (With BSA & Azide at 0.2mg/mL), 0.1 mg (With BSA & Azide at 0.2mg/mL), 0.1 mg (Without BSA & Azide at 1mg/mL), 5x 0.1 mg (With BSA & Azide at 0.2mg/mL), 5x 0.1 mg (Without BSA & Azide at 1mg/mL).

How many pack sizes does EME1 come in?

EME1 is available in 5 different pack sizes.

EME1 is currently made to order / not held in immediate stock. Contact us for lead time.

EME1

Product Specifications

Gene Name

[EME1]

NCBI Gene ID

146956

Reactivity

Human

Storage Conditions

Antibody with azide: store at 2 to 8 degree C.<br>Antibody without azide: store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

Essential meiotic endonuclease 1 (Eme1), a member of the Eme1/Mms4 family, associates with Mus81 to constitute a heterodimeric endonuclease that has been implicated in mitotic and meiotic recombination in eukaryotes. The Mus81-Eme1 complex cleaves branched DNA structures, especially those arising during stalled DNA replication such as replication forks and 3 DNA flaps. When purified from yeast, this complex cleaves synthetic Holliday junctions into linear duplex DNA. These findings provide compelling evidence that Mus81-Eme1 complexes are essential elements of the eukaryotic nuclear Holliday junction resolvase. Eme1 may also be required in mitosis for the processing of collapsed replication forks. Eme1 is typically localized to the nucleolus and is recruited to regions of DNA damage in S phase cells.

Other Gene Names

[EME1; EME1; MMS4L; SLX2A; MMS4; hMMS4]

Short Name

[EME1]

Other Product Names

[crossover junction endonuclease EME1 isoform 1; Crossover junction endonuclease EME1; crossover junction endonuclease EME1; essential meiotic structure-specific endonuclease 1; MMS4 homolog]