SERBP1/PAI-RBP1
Product Specifications
Gene Name
[SERBP1]
NCBI Gene ID
26135
Reactivity
Human
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.<br>Antibody without azide: store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
SERBP1 is a membrane-associated protein that localizes to the nucleus, the perinuclear region of the cytoplasm and the plasma membrane. It is believed to play a role in the regulation of mRNA stability, as it specifically binds to the CRS (cyclic nucleotide-responsive sequence) motif of the PAI-1 mRNA and acts to stabilize the mRNA and regulate its expression. In addition, SERBP1 interacts with Mi2-s antiapoptotic action in ovarian cell types. SERBP1 is overexpressed in ovarian cancer, suggesting a possible role in tumorigenesis and tumor metastasis.
Other Gene Names
[SERBP1; SERBP1; CGI-55; CHD3IP; HABP4L; PAIRBP1; PAI-RBP1; PAIRBP1; PAI-RBP1]
Short Name
[SERBP]
Other Product Names
[plasminogen activator inhibitor 1 RNA-binding protein isoform 1; Plasminogen activator inhibitor 1 RNA-binding protein; plasminogen activator inhibitor 1 RNA-binding protein; SERPINE1 mRNA binding protein 1; PAI1 RNA-binding protein 1; PAI-RBP1; SERPINE1 mRNA-binding protein 1]
NCBI GI Number
66346679
NCBI Accession Number
NP_001018077
NCBI GB Accession Number
NP_001018077.1
Uniprot Accession Number
Q8NC51
Available Sizes
Curated Selection
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