c-Myc Oncoprotein

Product Specifications

Gene Name

[MYC]

NCBI Gene ID

4609

Reactivity

Human<br>Does not react with Mouse, Rat, Chicken

Storage Conditions

Antibody with azide: store at 2 to 8 degree C.<br>Antibody without azide: store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

It recognizes a transcription factor of 64-67kDa, identified as c-myc. Its epitope spans between aa 410-419 (EQKLISEEDL) which is a specific portion of an alpha helical region of human c-myc protein. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease.

Other Gene Names

[MYC; MYC; MRTL; MYCC; c-Myc; bHLHe39; BHLHE39; bHLHe39]

Short Name

[c-Myc Oncoprotein]

Other Product Names

[myc proto-oncogene protein isoform 1; Myc proto-oncogene protein; myc proto-oncogene protein; MYC proto-oncogene, bHLH transcription factor; Class E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64]