SERBP1/PAI-RBP1

Antibody with azide: store at 2 to 8 degree C.<br>Antibody without azide: store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.

SERBP1 is a membrane-associated protein that localizes to the nucleus, the perinuclear region of the cytoplasm and the plasma membrane. It is believed to play a role in the regulation of mRNA stability, as it specifically binds to the CRS (cyclic nucleotide-responsive sequence) motif of the PAI-1 mRNA and acts to stabilize the mRNA and regulate its expression. In addition, SERBP1 interacts with Mi2-s antiapoptotic action in ovarian cell types. SERBP1 is overexpressed in ovarian cancer, suggesting a possible role in tumorigenesis and tumor metastasis.

[plasminogen activator inhibitor 1 RNA-binding protein isoform 1; Plasminogen activator inhibitor 1 RNA-binding protein; plasminogen activator inhibitor 1 RNA-binding protein; SERPINE1 mRNA binding protein 1; PAI1 RNA-binding protein 1; PAI-RBP1; SERPINE1 mRNA-binding protein 1]