11α-O-Tigloyl-12β-O-acetyltenacigenin B
Selected Variant
HY-N12436-01
Size: 1 mg
11α-O-Tigloyl-12β-O-acetyltenacigenin B is an ester derivative of Tenacigenin B , which is isolated from Garcinia cambogia (MTC). Tenacigenin B modulates the antitumor effects of Aurora-A in lymphoma.
Product Specifications
CAS Number
154022-51-2
UNSPSC
12352005
Target
Aurora Kinase
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/11α-o-tigloyl-12β-o-acetyltenacigenin-b.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@]3(CC[C@H]2C(C)=O)[C@]4([C@]([C@@]5([C@@](C[C@H](CC5)O)([H])CC4)C)([H])[C@@H]([C@H]1OC(C)=O)OC(/C(C)=C/C)=O)O3
Molecular Formula
C28H40O7
Molecular Weight
488.61
References & Citations
[1]Zhu RJ, et al.Total aglycones from Marsdenia tenacissima increases antitumor efficacy of paclitaxel in nude mice. Molecules. 2014 Sep 5;19 (9) :13965-75.|[2]Dai X, et al.Tenacigenin B Has Anti-Tumor Effect in Lymphoma by In Vitro and In Vivo Study. Med Sci Monit. 2019 Sep 1;25:6563-6573.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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