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NK1.1/CD161c/Klrb1c, Mouse

Product Specifications

Gene Name

[Klrb1c]

NCBI Gene ID

17059

Reactivity

Mouse<br>Does not react with Human.

Storage Conditions

Antibody with azide: store at 2 to 8 degree C.<br>Antibody without azide: store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

NK1.1 is a type II integral membrane glycoprotein with a C-type lectin domain and is encoded by theKlrb1c/NKR-P1Cgene.It is predominantly expressed as a disulfide-linked homodimer on NK cells however; it is also expressed on NK-T cells, a rare population of T lymphocytes.NK1.1 is expressed in some Mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cellsin vitroand rejection of bone marrow allograftsin vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN- production, and cytotoxic granule release. NK-1.1 is commonly used as a Mouse NK cell marker.

Other Gene Names

[Klrb1c; Klrb1c; Nk1; Ly59; Nk-1; CD161; Ly-59; Ly55c; NK1.1; NKRP1; Nk1.2; Klrb1b; NK-RP1; Nk-1.2; Nkrp1b; Nkrp1c; ly-55c; NKRP140; AI462337; NKR-P1.9; Ly55c; Nkrp1c; Ly-55c; NKR-P1 40]

Short Name

[NK1.1/CD161c/Klrb1c]

Other Product Names

[killer cell lectin-like receptor subfamily B member 1C isoform 1; Killer cell lectin-like receptor subfamily B member 1C; killer cell lectin-like receptor subfamily B member 1C; killer cell lectin-like receptor subfamily B member 1C; CD161 antigen-like family member C; Lymphocyte antigen 55c; Ly-55c; NK1.1; NKR-P1.9; NKR-P1C; Natural killer cell surface protein P1-40; NKR-P1 40; CD_antigen: CD161c]

NCBI GI Number

229577432

NCBI Accession Number

NP_001153376.1

NCBI GB Accession Number

NP_001153376.1

Uniprot Accession Number

P27814

Available Sizes

Curated Selection

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