CD2/Lymphocyte Function Antigen 2 (LFA-2)

Product Specifications

CAS Number

9007-83-4

Gene Name

[CD2/LFA-2]

NCBI Gene ID

914

Reactivity

Human

Storage Conditions

Antibody with azide: store at 4 to 8 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

Other Gene Names

[CD2; CD2; T11; SRBC; LFA-2; SRBC]

Short Name

[CD2/Lymphocyte Function Antigen 2 (LFA-2)]

Other Product Names

[T-cell surface antigen CD2 isoform 2; T-cell surface antigen CD2; T-cell surface antigen CD2; CD2 molecule; Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; CD_antigen: CD2]