Wilm's Tumor 1 (WT1) (Wilm's Tumor & Mesothelial Marker)
Product Specifications
Gene Name
[WT1]
NCBI Gene ID
7490
Reactivity
Human, Rat
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.<br>Antibody without azide: store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Recognizes a 47-55kDa-tumor suppressor protein, identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids, frequently found in subsets of sporadic Wilms tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the mesotheliomas.
Other Gene Names
[WT1; WT1; GUD; AWT1; WAGR; WT33; NPHS4; WIT-2]
Short Name
[Wilm's Tumor 1 (WT1)]
Other Product Names
[Wilms tumor protein isoform B; Wilms tumor protein; Wilms tumor protein; WT1 transcription factor; WT33]
NCBI GI Number
65507817
NCBI Accession Number
NP_077742.2
NCBI GB Accession Number
NP_077742.2
Uniprot Accession Number
P19544
Available Sizes
Curated Selection
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