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Ezrin/p81

Product Specifications

Gene Name

[EZR]

NCBI Gene ID

7430

Reactivity

Human

Storage Conditions

Antibody with azide: store at 2 to 8 degree C.<br>Antibody without azide: store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

Ezrin, Moesin and Radixin belong to a family of highly homologous Actinassociated proteins that are localized just beneath the plasma membrane. The proteins are believed to be involved in the mediation of interactions between cytoskeletal and membrane proteins. Ezrin serves as a major cytoplasmic substrate of various protein-tyrosine kinases, including the epidermal growth factor receptor. Ezrin has also been identified as a cAMP-dependent protein kinase (A-kinase) anchoring protein and designated AKAP78. Moesin and Radixin share over 70% homology with Ezrin and are coexpressed within various cell types. Despite the high degree of homology, the three proteins exhibit a distinct receptor-specific pattern of phosphorylation. Overexpression of Ezrin predicts the poor prognosis of gastric adenocarcinoma.

Other Gene Names

[EZR; EZR; CVL; CVIL; VIL2; HEL-S-105; VIL2]

Short Name

[Ezrin/p81]

Other Product Names

[ezrin; Ezrin; ezrin; ezrin; Cytovillin; Villin-2; p81]

NCBI GI Number

161702986

NCBI Accession Number

NP_001104547.1

NCBI GB Accession Number

NP_001104547.1

Uniprot Accession Number

P15311

Available Sizes

Frequently Asked Questions

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