Trefoil Factor 2/TFF2
Product Specifications
Gene Name
[TFF2]
NCBI Gene ID
7032
Reactivity
Human
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.<br>Antibody without azide: store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. pS2, also designated Md2, BCEI, TFF1 and pNR-2, is a trefoil protein that is highly expressed in normal gastric mucosa. pS2 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. pS2 is not present in normal breast tissue but is inducible by estrogen in MCF7 cells. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. The gene encoding pS2 maps to human chromosome 21q22.3.
Other Gene Names
[TFF2; TFF2; SP; SML1; SML1; SP]
Short Name
[Trefoil Factor 2/TFF2]
Other Product Names
[trefoil factor 2; Trefoil factor 2; trefoil factor 2; trefoil factor 2; Spasmolysin; Spasmolytic polypeptide]
NCBI GI Number
4885629
NCBI Accession Number
NP_005414.1
NCBI GB Accession Number
NP_005414.1
Uniprot Accession Number
Q03403
Available Sizes
Curated Selection
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