STAT2
Product Specifications
Gene Name
[STAT2]
NCBI Gene ID
6773
Reactivity
Human
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.<br>Antibody without azide: store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN- is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.
Other Gene Names
[STAT2; STAT2; P113; IMD44; ISGF-3; STAT113]
Short Name
[STAT2]
Other Product Names
[signal transducer and activator of transcription 2 isoform 1; Signal transducer and activator of transcription 2; signal transducer and activator of transcription 2; signal transducer and activator of transcription 2; p113]
NCBI GI Number
4885615
NCBI Accession Number
NP_005410.1
NCBI GB Accession Number
NP_005410.1
Uniprot Accession Number
P52630
Available Sizes
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