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MUC2 (Mucin 2)

Product Specifications

Gene Name

[MUC2]

NCBI Gene ID

4583

Reactivity

Human

Storage Conditions

Antibody with azide: store at 2 to 8 degree C.<br>Antibody without azide: store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as GTQTP (GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.

Other Gene Names

[MUC2; MUC2; MLP; SMUC; MUC-2; SMUC; MUC-2]

Short Name

[MUC2 (Mucin 2)]

Other Product Names

[mucin-2; Mucin-2; mucin-2; mucin 2, oligomeric mucus/gel-forming; Intestinal mucin-2]

NCBI GI Number

116284392

NCBI Accession Number

NP_002448.2

NCBI GB Accession Number

NP_002448.2

Uniprot Accession Number

Q02817

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