Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker)
Product Specifications
Gene Name
[KRT15]
NCBI Gene ID
3866
Reactivity
Human
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.<br>Antibody without azide: store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins.
Other Gene Names
[KRT15; KRT15; K15; CK15; K1CO; KRTB; CK-15; K15]
Short Name
[Cytokeratin 15]
Other Product Names
[keratin, type I cytoskeletal 15; Keratin, type I cytoskeletal 15; keratin, type I cytoskeletal 15; keratin 15; Cytokeratin-15; CK-15; Keratin-15]
NCBI GI Number
24430190
NCBI Accession Number
NP_002266.2
NCBI GB Accession Number
NP_002266.2
Uniprot Accession Number
P19012
Available Sizes
Curated Selection
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