Prostate Specific Antigen (PSA)

Product Specifications

CAS Number

9007-83-4

Gene Name

[PSA]

NCBI Gene ID

354

Reactivity

Human

Storage Conditions

Antibody with azide: store at 2 to 8 degree C.<br>Antibody without azide: store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb A67-B/E3 for PSA tests.

Other Gene Names

[KLK3; KLK3; APS; PSA; hK3; KLK2A1; APS; PSA; Seminin]

Short Name

[Prostate Specific Antigen (PSA)]

Other Product Names

[prostate-specific antigen isoform 3 preproprotein; Prostate-specific antigen; prostate-specific antigen; kallikrein related peptidase 3; Gamma-seminoprotein; Seminin; Kallikrein-3; P-30 antigen; Semenogelase]