Lambda Light Chain (B-Cell Marker)
Product Specifications
Gene Name
[IGL]
Reactivity
Human
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.<br>Antibody without azide: store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Short Name
[Lambda Light Chain]
Other Product Names
[Ig lambda chain V-I region NEW; Ig lambda chain V-I region NEW]
NCBI GI Number
126541
NCBI Accession Number
P01701.1
Uniprot Accession Number
P01701
Available Sizes
Frequently Asked Questions
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