Tenascin C (Stromal Marker for Epithelial Malignancy)
Product Specifications
Gene Name
[TNC]
NCBI Gene ID
3371
Reactivity
Human<br>Does not react with Rat.
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.<br>Antibody without azide: store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
In Western blotting, it reacts with two bands of ~MW of 210kDa and 300kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linkedhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.
Other Gene Names
[TNC; TNC; GP; JI; TN; HXB; GMEM; TN-C; DFNA56; 150-225; HXB; TN; TN-C]
Short Name
[Tenascin C]
Other Product Names
[tenascin; Tenascin; tenascin; tenascin C; Cytotactin; GMEM; GP 150-225; Glioma-associated-extracellular matrix antigen; Hexabrachion; JI; Myotendinous antigen; Neuronectin; Tenascin-C]
NCBI GI Number
153946395
NCBI Accession Number
NP_002151.2
NCBI GB Accession Number
NP_002151.2
Uniprot Accession Number
P24821
Available Sizes
Curated Selection
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