Annexin A1/(Hairy Cell Leukemia Marker)
Product Specifications
Gene Name
[ANXA1]
NCBI Gene ID
301
Reactivity
Human
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.<br>Antibody without azide: store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.
Other Gene Names
[ANXA1; ANXA1; ANX1; LPC1; ANX1; LPC1]
Short Name
[Annexin A1]
Other Product Names
[annexin A1; Annexin A1; annexin A1; annexin A1; Annexin I; Annexin-1; Calpactin II; Calpactin-2; Chromobindin-9; Lipocortin I; Phospholipase A2 inhibitory protein; p35]
NCBI GI Number
4502101
NCBI Accession Number
NP_000691.1
NCBI GB Accession Number
NP_000691.1
Uniprot Accession Number
P04083
Available Sizes
Curated Selection
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