PD-L1/PDCD1LG1/CD274/B7-H1 (Cancer Immunotherapy Target)
Product Specifications
Gene Name
[CD274]
NCBI Gene ID
29126
Reactivity
Human
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.<br>Antibody without azide: store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.
Other Gene Names
[CD274; CD274; B7-H; B7H1; PDL1; PD-L1; hPD-L1; PDCD1L1; PDCD1LG1; B7H1; PDCD1L1; PDCD1LG1; PDL1; PD-L1; PDCD1 ligand 1; Programmed death ligand 1; B7-H1]
Short Name
[PD-L1/PDCD1LG1/CD274/B7-H1]
Other Product Names
[programmed cell death 1 ligand 1 isoform b; Programmed cell death 1 ligand 1; programmed cell death 1 ligand 1; CD274 molecule; B7 homolog 1]
NCBI GI Number
390979639
NCBI Accession Number
NP_001254635.1
NCBI GB Accession Number
NP_001254635.1
Uniprot Accession Number
Q9NZQ7
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