Frataxin (Mitochondrial Marker)
Product Specifications
Gene Name
[FXN]
NCBI Gene ID
2395
Reactivity
Human
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.<br>Antibody without azide: store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.
Other Gene Names
[FXN; FXN; FA; X25; CyaY; FARR; FRDA; FRDA; X25; Fxn; i-FXN]
Short Name
[Frataxin]
Other Product Names
[Frataxin, mitochondrial; Frataxin, mitochondrial; frataxin, mitochondrial; frataxin; Friedreich ataxia protein; Fxn]
NCBI GI Number
6166193
NCBI Accession Number
Q16595.2
Uniprot Accession Number
Q16595
Available Sizes
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