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Frataxin (Mitochondrial Marker)

Product Specifications

Gene Name

[FXN]

NCBI Gene ID

2395

Reactivity

Human

Storage Conditions

Antibody with azide: store at 2 to 8 degree C.<br>Antibody without azide: store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.

Other Gene Names

[FXN; FXN; FA; X25; CyaY; FARR; FRDA; FRDA; X25; Fxn; i-FXN]

Short Name

[Frataxin]

Other Product Names

[Frataxin, mitochondrial; Frataxin, mitochondrial; frataxin, mitochondrial; frataxin; Friedreich ataxia protein; Fxn]

NCBI GI Number

6166193

NCBI Accession Number

Q16595.2

Uniprot Accession Number

Q16595

Available Sizes

Frequently Asked Questions

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