EGFR (Epidermal Growth Factor Receptor)

Product Specifications

Gene Name

[EGFR]

NCBI Gene ID

1956

Reactivity

Human<br>Does not react with Mouse.

Storage Conditions

Antibody with azide: store at 4 to 8 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Other Gene Names

[EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; ERBB; ERBB1; HER1]

Short Name

[EGFR (Epidermal Growth Factor Receptor)]

Other Product Names

[epidermal growth factor receptor isoform a; Epidermal growth factor receptor; epidermal growth factor receptor; epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1]