Drebrin 1 (DBN1)
Product Specifications
Gene Name
[DBN1]
NCBI Gene ID
1627
Reactivity
Human
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.<br>Antibody without azide: store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2); and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer s disease and Down syndrome.
Other Gene Names
[DBN1; DBN1; D0S117E; D0S117E]
Short Name
[Drebrin 1 (DBN1)]
Other Product Names
[drebrin isoform a; Drebrin; drebrin; drebrin 1; Developmentally-regulated brain protein]
NCBI GI Number
18426915
NCBI Accession Number
NP_004386.2
NCBI GB Accession Number
NP_004386.2
Uniprot Accession Number
Q16643
Available Sizes
Curated Selection
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