Chromogranin A/CHGA (Neuroendocrine Marker)
Product Specifications
Gene Name
[CHGA]
NCBI Gene ID
1113
Reactivity
Human
Storage Conditions
Antibody with azide: store at 4 to 8 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin A.
Other Gene Names
[CHGA; CHGA; CGA; CgA; SP-I]
Short Name
[Chromogranin A/CHGA]
Other Product Names
[chromogranin-A isoform 1 preproprotein; Chromogranin-A; chromogranin-A; chromogranin A; Pituitary secretory protein I; SP-ICleaved into the following 13 chains:Vasostatin-1; Alternative name(s):; Vasostatin IVasostatin-2; Alternative name(s):; Vasostatin II]
NCBI GI Number
4502805
NCBI Accession Number
NP_001266.1
NCBI GB Accession Number
NP_001266.1
Uniprot Accession Number
P10645
Available Sizes
Curated Selection
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