Cdk2/p34cdc2 Serine-Threonine Kinase
Product Specifications
Gene Name
[CDK2]
NCBI Gene ID
1017
Reactivity
Human, Mouse, Xenopus
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.<br>Antibody without azide: store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
In vertebrates, as in yeast, multiple cyclins have been identified, including a total of eight such regulatory proteins in mammals. In contrast to the situation in yeast, the Cdc2 p34 kinase is not the only catalytic subunit identified in vertebrates that can interact with cyclins. While Cdc2 p34 is essential for the G2 to M transition in vertebrate cells, a second Cdc2-related kinase has also been implicated in cell cycle control. This protein, designated cyclindependent kinase 2 (Cdk2), also binds to cyclins and its kinase activity is temporally regulated during the cell cycle. Several additional Cdc2-related cyclin dependent kinases have been identified. These include Cdk3, Cdk4, Cdk5, PCTAIRE-1, PCTAIRE-2, PCTAIRE-3, Cdk6 Cdk7, Cdk8 and KKIALRE.
Other Gene Names
[CDK2; CDK2; CDKN2; p33(CDK2); CDKN2]
Short Name
[Cdk2/p34cdc2 Serine-Threonine Kinase]
Other Product Names
[cyclin-dependent kinase 2 isoform 1; Cyclin-dependent kinase 2; cyclin-dependent kinase 2; cyclin dependent kinase 2; Cell division protein kinase 2; p33 protein kinase]
NCBI GI Number
16936528
NCBI Accession Number
NP_001789.2
NCBI GB Accession Number
NP_001789.2
Uniprot Accession Number
P24941
Available Sizes
Curated Selection
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