HNF1A (Pancreatic Tumor Suppressor)

Antibody with azide: store at 2 to 8°C.<br>Antibody without azide: store at -20 to -80°C.<br>Antibody is stable for 12 months. Non-hazardous. No MSDS required.

HNF1A belongs to the homeobox protein family and is an essential transcription factor for many hepatic genes involved in detoxification, homeostasis and metabolisms of glucose, lipid, steroid and amino acid. In addition, HNF1A is an important component of the transcriptional networks governing embryonic pancreas development and differentiation. as well as maintaining the growth and function of islet beta cells in adult. HNF1A (Hepatocyte nuclear factor 1 alpha) is a transcription factor that is known to regulate pancreatic differentiation and maintain homeostasis of endocrine pancreas. Recently, genome-wide association studies have implicated HNF1A as a susceptibility gene for pancreatic cancer.

[hepatocyte nuclear factor 1-alpha isoform 2; Hepatocyte nuclear factor 1-alpha; hepatocyte nuclear factor 1-alpha; HNF1 homeobox A; Liver-specific transcription factor LF-B1; LFB1; Transcription factor 1; TCF-1]