Replication Protein A2 (RPA2)
Product Specifications
Gene Name
[RPA2]
NCBI Gene ID
6118
Reactivity
Human. Others not known.
Storage Conditions
Antibody with azide - store at 2 to 8 degree C.<br>Antibody without azide - store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Recognizes a protein of 34kDa, identified as a subunit of Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB). RPA from human cells is a stable heterotrimer of 70kDa, 32-34kDa, and 11-14kDa subunits (RPA70, RPA32, and RPA14 respectively). It is involved in DNA replication, repair, and recombination. RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase (pol) alpha and delta. RPA34 is phosphorylated at the G1/S boundary of the cell cycle or upon exposure of cells to DNA damage-inducing agents including ionizing and UV radiation.
Other Gene Names
[RPA2; RPA2; REPA2; RPA32; RP-A p32; RP-A p34; REPA2; RPA32; RPA34; RP-A p32; RF-A protein 2; RP-A p34]
Short Name
[Replication Protein A2 (RPA2)]
Other Product Names
[replication protein A 32 kDa subunit isoform 2; Replication protein A 32 kDa subunit; replication protein A 32 kDa subunit; replication protein A2; Replication factor A protein 2; RF-A protein 2; Replication protein A 34 kDa subunit; RP-A p34]
NCBI GI Number
554595586
NCBI Accession Number
NP_001273005.1
NCBI GB Accession Number
NM_001286076.1
Uniprot Accession Number
P15927
Available Sizes
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