PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein)
Product Specifications
Gene Name
[PMEPA1]
NCBI Gene ID
56937
Reactivity
Human. Others not known.
Storage Conditions
Antibody with azide - store at 2 to 8 degree C.<br>Antibody without azide - store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.
Other Gene Names
[PMEPA1; STAG1; TMEPAI]
Short Name
[PMEPA1/TMEPAI]
Other Product Names
[protein TMEPAI; prostate transmembrane protein, androgen induced 1]
Uniprot Accession Number
Q96W9
Available Sizes
Curated Selection
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