Prostate Specific Antigen (PSA)
Product Specifications
CAS Number
9007-83-4
Gene Name
[PSA]
NCBI Gene ID
354
Reactivity
Human. Others not known.
Storage Conditions
Antibody with azide - store at 2 to 8 degree C.<br>Antibody without azide - store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb A67-B/E3 for PSA tests.
Other Gene Names
[KLK3; KLK3; APS; PSA; hK3; KLK2A1; APS; PSA; Seminin]
Short Name
[Prostate Specific Antigen (PSA)]
Other Product Names
[prostate-specific antigen isoform 3 preproprotein; Prostate-specific antigen; prostate-specific antigen; kallikrein related peptidase 3; Gamma-seminoprotein; Seminin; Kallikrein-3; P-30 antigen; Semenogelase]
NCBI GI Number
71834853
NCBI Accession Number
NP_001025218.1
NCBI GB Accession Number
NM_001030047.1
Uniprot Accession Number
P07288
Available Sizes
Curated Selection
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