Heregulin-1/Neuregulin-1 (Breast and Urothelial Marker)
Product Specifications
Gene Name
[NRG1]
NCBI Gene ID
3084
Reactivity
Human. Others not known.
Storage Conditions
Antibody with azide - store at 2 to 8 degree C.<br>Antibody without azide - store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Heregulin-1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).
Other Gene Names
[NRG1; NRG1; GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; MSTP131; NRG1-IT2; GGF; HGL; HRGA; NDF; SMDF; Pro-NRG1; ARIA; HRG]
Short Name
[Heregulin-1/Neuregulin-1]
Other Product Names
[pro-neuregulin-1, membrane-bound isoform isoform HRG-beta1c; Pro-neuregulin-1, membrane-bound isoform; pro-neuregulin-1, membrane-bound isoform; neuregulin 1; Neuregulin-1Alternative name(s):Acetylcholine receptor-inducing activity; ARIA]
NCBI GI Number
236461509
NCBI Accession Number
NP_001153467.1
NCBI GB Accession Number
NM_001159995.2
Uniprot Accession Number
Q02297
Available Sizes
Curated Selection
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