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Heregulin-1/Neuregulin-1 (Breast and Urothelial Marker)

Product Specifications

Gene Name

[NRG1]

NCBI Gene ID

3084

Reactivity

Human. Others not known.

Storage Conditions

Antibody with azide - store at 2 to 8 degree C.<br>Antibody without azide - store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

Heregulin-1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).

Other Gene Names

[NRG1; NRG1; GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; MSTP131; NRG1-IT2; GGF; HGL; HRGA; NDF; SMDF; Pro-NRG1; ARIA; HRG]

Short Name

[Heregulin-1/Neuregulin-1]

Other Product Names

[pro-neuregulin-1, membrane-bound isoform isoform HRG-beta1c; Pro-neuregulin-1, membrane-bound isoform; pro-neuregulin-1, membrane-bound isoform; neuregulin 1; Neuregulin-1Alternative name(s):Acetylcholine receptor-inducing activity; ARIA]

NCBI GI Number

236461509

NCBI Accession Number

NP_001153467.1

NCBI GB Accession Number

NM_001159995.2

Uniprot Accession Number

Q02297

Available Sizes

Curated Selection

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