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ATG5 (Autophagy Marker)

Product Specifications

Gene Name

[ATG5]

NCBI Gene ID

9474

Reactivity

Human. Others not known.

Specificity

The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. The ATG5 protein is essential for autophagy; a process that is usually beneficial for cells to self-degrade their own components when they are no longer useful.

Other Gene Names

[ATG5; ATG5; ASP; APG5; APG5L; hAPG5; SCAR25; APG5-LIKE; APG5L; ASP]

Short Name

[ATG5]

Other Product Names

[autophagy protein 5 isoform a; Autophagy protein 5; autophagy protein 5; autophagy related 5; APG5-like; Apoptosis-specific protein]

NCBI GI Number

554790362

NCBI Accession Number

NP_001273035.1

NCBI GB Accession Number

NM_001286106.1

Uniprot Accession Number

Q9H1Y0

Available Sizes

Frequently Asked Questions

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