TCF4 (Transcription Factor 4)

Product Specifications

Gene Name

[TCF4]

NCBI Gene ID

6925

Reactivity

Human. Others not tested.

Specificity

Recognizes a protein of 71kDa, identified as Transcription Factor 4 (TCF4). It is a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome.

Other Gene Names

[TCF4; TCF4; E2-2; ITF2; PTHS; SEF2; FECD3; ITF-2; SEF-2; TCF-4; SEF2-1; SEF2-1A; SEF2-1B; SEF2-1D; bHLHb19; BHLHB19; ITF2; SEF2; TCF-4; bHLHb19; ITF-2; SEF-2]

Short Name

[TCF4 (Transcription Factor 4)]

Other Product Names

[transcription factor 4 isoform a; Transcription factor 4; transcription factor 4; transcription factor 4; Class B basic helix-loop-helix protein 19; bHLHb19; Immunoglobulin transcription factor 2; ITF-2; SL3-3 enhancer factor 2; SEF-2]