BOB.1 (B-Cell Marker)
Product Specifications
Gene Name
[BOB.1]
NCBI Gene ID
5450
Reactivity
Human. Others not known.
Specificity
BOB.1 expression in a variety of established B-cell lines, representing different stages of B-cell development, has suggested a constitutive, B-cell-specific expression pattern. LP cells in nodular lymphocyte predominant Hodgkin lymphoma, because they are germinal center-derived, are consistently immuno-positive for BOB.1. Conversely, only some cases of classical Hodgkin lymphoma show BOB.1 immuno-reactivity within the Hodgkin and Reed-Sternberg cells. Expression of BOB.1 has been reported in follicular center cell lymphoma, diffuse large B-cell lymphoma and some cases of acute myeloid leukemia. B-CLL, marginal zone lymphoma, and mantle cell lymphoma may show weak to moderate immunoreactivity.
Other Gene Names
[POU2AF1; POU2AF1; BOB1; OBF1; OCAB; OBF-1; OBF1]
Short Name
[BOB.1]
Other Product Names
[POU domain class 2-associating factor 1; POU domain class 2-associating factor 1; POU domain class 2-associating factor 1; POU class 2 associating factor 1; B-cell-specific coactivator OBF-1; BOB-1; OCA-B; OCT-binding factor 1]
NCBI GI Number
167900478
NCBI Accession Number
NP_006226.2
NCBI GB Accession Number
NM_006235.2
Uniprot Accession Number
Q16633
Available Sizes
Curated Selection
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