PTEN (Tumor Suppressor Oncoprotein)
Product Specifications
Gene Name
[PTEN]
NCBI Gene ID
5728
Reactivity
Human. Others not known.
Specificity
PTEN (phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase) contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. It was identified as a tumor suppressor that is mutated in a large number of cancers, including sporadic brain, breast, kidney, and prostate cancers.
Other Gene Names
[PTEN; PTEN; BZS; DEC; CWS1; GLM2; MHAM; TEP1; MMAC1; PTEN1; 10q23del; PTENbeta; MMAC1; TEP1]
Short Name
[PTEN]
Other Product Names
[phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform PTEN; Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatase and tensin homolog; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog]
NCBI GI Number
73765544
NCBI Accession Number
NP_000305.3
NCBI GB Accession Number
NM_000314.6
Uniprot Accession Number
P60484
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