PAX5/BSAP (Early B-Cell Marker)
Product Specifications
Gene Name
[PAX5]
NCBI Gene ID
5079
Reactivity
Human. Others not tested.
Specificity
The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19, 000, full-length human proteins. The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis; therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.
Other Gene Names
[PAX5; PAX5; ALL3; BSAP; BSAP]
Short Name
[PAX5/BSAP]
Other Product Names
[paired box protein Pax-5 isoform 2; Paired box protein Pax-5; paired box protein Pax-5; paired box 5; B-cell-specific transcription factor; BSAP]
NCBI GI Number
525507346
NCBI Accession Number
NP_001267476.1
NCBI GB Accession Number
NP_001267476.1
Uniprot Accession Number
Q02548
Available Sizes
Curated Selection
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