CD10 (Membrane Metalloendopeptidase)
Product Specifications
Gene Name
[CD10]
NCBI Gene ID
4311
Reactivity
Human. Others not tested.
Specificity
Recognizes a 100kDa glycoprotein, identified as CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.
Other Gene Names
[MME; MME; NEP; SFE; CD10; CALLA; CMT2T; SCA43; EPN; CALLA; NEP; Neutral endopeptidase; SFE]
Short Name
[CD10]
Other Product Names
[neprilysin isoform a; Neprilysin; neprilysin; membrane metalloendopeptidase; Atriopeptidase; Common acute lymphocytic leukemia antigen; CALLA; Enkephalinase; Neutral endopeptidase 24.11; NEP; Neutral endopeptidase; Skin fibroblast elastase; SFE; CD_antigen: CD10]
NCBI GI Number
116256329
NCBI Accession Number
NP_000893.2
NCBI GB Accession Number
NM_000902.3
Uniprot Accession Number
P08473
Available Sizes
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