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Cytokeratin 8/18

Product Specifications

Gene Name

[KRT8]

NCBI Gene ID

3856

Reactivity

Human. Others not known.

Storage Conditions

Antibody with azide - store at 2 to 8 degree C.<br>Antibody without azide - store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.

Other Gene Names

[KRT8; KRT8; K8; KO; CK8; CK-8; CYK8; K2C8; CARD2; CYK8; CK-8; K8]

Short Name

[Cytokeratin 8/18]

Other Product Names

[keratin, type II cytoskeletal 8 isoform 2; Keratin, type II cytoskeletal 8; keratin, type II cytoskeletal 8; keratin 8; Cytokeratin-8; CK-8; Keratin-8; K8; Type-II keratin Kb8]

NCBI GI Number

372466577

NCBI Accession Number

NP_001243222.1

NCBI GB Accession Number

NM_001256293.1

Uniprot Accession Number

P05787

Available Sizes

Frequently Asked Questions

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