CD79b (B-Cell Marker)
Product Specifications
Gene Name
[CD79b]
NCBI Gene ID
974
Reactivity
Human. Others not known.
Storage Conditions
Antibody with azide - store at 2 to 8 degree C.<br>Antibody without azide - store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
CD79 (also designated Ig ?/Ig ?) is a heterodimer composed of ? chains, designated CD79A or MB-1, and ? chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.
Other Gene Names
[CD79B; CD79B; B29; IGB; AGM6; B29; IGB]
Short Name
[CD79b]
Other Product Names
[B-cell antigen receptor complex-associated protein beta chain isoform 1; B-cell antigen receptor complex-associated protein beta chain; B-cell antigen receptor complex-associated protein beta chain; CD79b molecule; B-cell-specific glycoprotein B29; Ig-beta; Immunoglobulin-associated B29 protein; CD_antigen: CD79b]
NCBI GI Number
11038674
NCBI Accession Number
NP_000617.1
NCBI GB Accession Number
NM_000626.3
Uniprot Accession Number
P40259
Available Sizes
Curated Selection
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