CD34 (Hematopoietic Stem Cell & Endothelial Marker)
Product Specifications
Gene Name
[CD34]
NCBI Gene ID
947
Reactivity
Human, Rat. Others not known.
Storage Conditions
Antibody with azide - store at 2 to 8 degree C.<br>Antibody without azide - store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
This antibody recognizes a transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposis sarcoma, but shows low specificity.
Other Gene Names
[CD34; CD34]
Short Name
[CD34]
Other Product Names
[hematopoietic progenitor cell antigen CD34 isoform a; Hematopoietic progenitor cell antigen CD34; hematopoietic progenitor cell antigen CD34; CD34 molecule; CD_antigen: CD34]
NCBI GI Number
68342038
NCBI Accession Number
NP_001020280.1
NCBI GB Accession Number
NM_001025109.1
Uniprot Accession Number
P28906
Available Sizes
Curated Selection
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