CD27 (Tumor Necrosis Factor Receptor Superfamily 7)

Product Specifications

Gene Name

[CD27]

NCBI Gene ID

939

Reactivity

Human. Others not tested.

Storage Conditions

Antibody with azide - store at 2 to 8 degree C.<br>Antibody without azide - store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFkB and SAPK/JNK and induces apoptosis.

Other Gene Names

[CD27; CD27; T14; S152; Tp55; TNFRSF7; S152. LPFS2; TNFRSF7]

Short Name

[CD27]

Other Product Names

[CD27 antigen; CD27 antigen; CD27 antigen; CD27 molecule; CD27L receptor; T-cell activation antigen CD27; T14; Tumor necrosis factor receptor superfamily member 7; CD_antigen: CD27]